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Extra resources for Adapted Stories by O. Henry

Sample text

Specific adhesion allows for competition between normal flora and group A streptococci for tissue sites where normal flora reside. Streptococcal adhesion requires multiple group A streptococcal adhesins reported by several investigators and described in excellent reviews (Hasty et al. 1992; Hasty and Courtney 1996; Cunningham 2000; Courtney et al. 2002; Bisno et al. 2003). Adherence involves a two step process whereby weak interaction with the mucosa initiates adhesion and is followed by stronger adherence to tissue specific, high avidity ligands.

Coovadia and I. Coovadia The year preceding the XIII International AIDS Conference in Durban, South Africa, had been marked by an escalation of the government’s rhetoric which challenged critical issues on HIV/AIDS. In October 1999 President Thabo Mbeki had disputed the use of AZT for the prevention of MTCT of HIV; yet AZT had been shown conclusively to reduce MTCT by almost two-thirds. President Mbeki pointed to legal cases pending in the UK and US against AZT: “There also exists a large volume of literature alleging that….

Lancet Infect Dis, 3:191–200. Chatellier S, Ihendyane N, Kansal RG, Khambaty F, Basma H, Norrby-Teglund A, Low DE, McGeer A, and Kotb M. (2000). Genetic relatedness and superantigen expression in group A streptococcus serotype M1 isolates from patients with severe and nonsevere invasive diseases. Infect Immun, 68:3523–3534. Cleary P, Prabu U, Dale J, Wexler D, and Handley J. (1992). Streptococcal C5a peptidase is a highly specific endopeptidase. Infect Immun, 60:5219–5223. Courtney HS, Hasty DL, and Dale JB.

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Adapted Stories by O. Henry

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